Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/153
Título: Experimental evolution reveals natural selection on standing genetic variation
Autor: Teotónio, H
Chelo, IM
Bradic, M
Rose, MR
Long, AD
Palavras-chave: EFFECTIVE POPULATION-SIZE
DROSOPHILA-MELANOGASTER
REVERSE EVOLUTION
ADAPTATION
POLYMORPHISMS
FIXATION
Data: Fev-2009
Editora: Nature
Citação: Teotónio H., Chelo IM., Bradic, M., Rose, MR., Long, AD. (2009). “Experimental evolution reveals natural selection on standing genetic variation”. Nature Genetics. 41 (2): 251-257
Resumo: Evolution depends on genetic variation generated by mutation or recombination from standing genetic variation. In sexual organisms, little is known about the molecular population genetics of adaptation and reverse evolution(1-11). We carry out 50 generations of experimental reverse evolution in populations of Drosophila melanogaster, previously differentiated by forward evolution, and follow changes in the frequency of SNPs in both arms of the third chromosome. We characterize the effects of sampling finite population sizes and natural selection at the genotype level. We demonstrate that selection has occurred at several loci and further that there is no general loss or gain of allele diversity. We also observe that despite the complete convergence to ancestral levels of adaptation, allele frequencies only show partial return.
URI: http://hdl.handle.net/10400.7/153
ISSN: 1061-4036
Aparece nas colecções:EG - Artigos

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