Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/387
Título: The roles of juvenile hormone, insulin/target of rapamycin, and ecydsone signaling in regulating body size inDrosophila
Autor: Mirth, Christen Kerry
Shingleton, Alexander William
Palavras-chave: body size
growth rate
growth duration
juvenile hormone
ecdysone
insulin/insulin-like growth factor signalling
Data: 31-Out-2014
Editora: Taylor & Francis Group
Citação: Christen Kerry Mirth & Alexander William Shingleton (2014) The roles of juvenile hormone, insulin/target of rapamycin, and ecydsone signaling in regulating body size in Drosophila, Communicative & Integrative Biology, 7:5, 1-3, DOI: 10.4161/cib.29240
Resumo: Understanding how organisms regulate their body size has interested biologists for decades. Recent work has shown that both insulin/target of rapamycin (TOR) signaling and the steroid hormone ecdysone act to regulate rates of growth and the duration of the growth period in the fruit fly, Drosophila melanogaster. Our recent work has uncovered a third level of interaction, whereby juvenile hormone (JH) regulates levels of both ecdysone and insulin/TOR signaling to control growth rates. These studies highlight a complex network of interactions involved in regulating body and organ size.
Peer review: yes
URI: http://hdl.handle.net/10400.7/387
DOI: 10.4161/cib.29240
10.4161/cib.29240
10.4161/cib.29240
Versão do Editor: http://www.tandfonline.com/doi/full/10.4161/cib.29240
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