Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/413
Título: Asymptomatic Plasmodium falciparum infection in children is associated with increased auto-antibody production, high IL-10 plasma levels and antibodies to merozoite surface protein 3
Autor: Guiyedi, Vincent
Bécavin, Christophe
Herbert, Fabien
Gray, Julian
Cazenave, Pierre-André
Kombila, Maryvonne
Crisanti, Andrea
Fesel, Constantin
Pied, Sylviane
Palavras-chave: Auto-antibody
Antibody response
Plasmodium falciparum
Malaria
Cytokines
Data: 16-Abr-2015
Editora: BioMed Central
Resumo: Mechanisms of acquired protection to malaria in asymptomatic Plasmodium falciparum carriers are only partially understood. Among them, the role plays by the self-reactive antibodies has not been clarified yet. In this study, the relationship between repertoires of circulating self-reactive and parasite-specific immunoglobulin G (IgG), their correlation with cytokine levels, and their association with protection against malaria was investigated in asymptomatic Plasmodium falciparum-infected Gabonese children.
Peer review: yes
URI: http://hdl.handle.net/10400.7/413
DOI: 10.1186/s12936-015-0658-7
Versão do Editor: http://www.malariajournal.com/content/14/1/162
Aparece nas colecções:LAIR articles

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