Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/416
Título: INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community
Autor: Meehan, T.F.
Demengeot, Jocelyne
44 colaborators, Infrafrontier Consortium
Data: 3-Nov-2014
Editora: Oxford University Press
Citação: The 2015 Nucleic Acids Research Database Issue and Molecular Biology Database Collection Nucleic Acids Res (2015) 43 (D1): D1-D5
Resumo: The laboratory mouse is a key model organism to investigate mechanism and therapeutics of human disease. The number of targeted genetic mouse models of disease is growing rapidly due to high-throughput production strategies employed by the International Mouse Phenotyping Consortium (IMPC) and the development of new, more efficient genome engineering techniques such as CRISPR based systems. We have previously described the European Mouse Mutant Archive (EMMA) resource and how this international infrastructure provides archiving and distribution worldwide for mutant mouse strains. EMMA has since evolved into INFRAFRONTIER (http://www.infrafrontier.eu), the pan-European research infrastructure for the systemic phenotyping, archiving and distribution of mouse disease models. Here we describe new features including improved search for mouse strains, support for new embryonic stem cell resources, access to training materials via a comprehensive knowledgebase and the promotion of innovative analytical and diagnostic techniques.
Peer review: yes
URI: http://hdl.handle.net/10400.7/416
DOI: 10.1093/nar/gku1193
Versão do Editor: http://nar.oxfordjournals.org/content/43/D1/D1171.long#fn-group-1
Aparece nas colecções:LP - Artigos

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