Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/428
Título: Q&A: Who needs a centrosome?
Autor: Bettencourt-Dias, Mónica
Palavras-chave: Centrosome
Data: 11-Abr-2013
Editora: BioMed Central
Citação: Bettencourt-Dias M: Q&A: Who needs a centrosome?. BMC Biology 2013 11:28.
Resumo: The centrosome has several functions. The central one is as the major microtubule organizing center (MTOC) in proliferating animal cells: thus, it helps to organize the microtubules that form the mitotic spindle in dividing cells, and orchestrate a wide variety of cellular processes, including cell motility, signaling, adhesion, coordination of protein trafficking by the microtubule cytoskeleton and the acquisition of polarity. The centrosome has crucial links to the nucleus, the Golgi, cell to cell junctions and acto-myosin cytoskeleton that are very important in positioning it and thus shaping the microtubule cytoskeleton in relation to the cell and the organism (reviewed in [1]). The role of the centrosome in organizing cellular microtubules can differ from cell to cell and be regulated differently in different phases of the life of a cell.
Peer review: yes
URI: http://hdl.handle.net/10400.7/428
DOI: 10.1186/1741-7007-11-28
Versão do Editor: http://www.biomedcentral.com/1741-7007/11/28
Aparece nas colecções:CCR - Artigos

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
1741-7007-11-28.pdfartigo principal626,15 kBAdobe PDFVer/Abrir


FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.