Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/589
Título: Ensembl regulation resources
Autor: Zerbino, Daniel R.
Johnson, Nathan
Juetteman, Thomas
Sheppard, Dan
Wilder, Steven P.
Lavidas, Ilias
Nuhn, Michael
Perry, Emily
Raffaillac-Desfosses, Quentin
Sobral, Daniel
Keefe, Damian
Gräf, Stefan
Ahmed, Ikhlak
Kinsella, Rhoda
Pritchard, Bethan
Brent, Simon
Amode, Ridwan
Parker, Anne
Trevanion, Steven
Birney, Ewan
Dunham, Ian
Flicek, Paul
Palavras-chave: Genome
Data: 24-Nov-2015
Editora: Oxford University Press
Citação: Zerbino, D.R., Johnson, N., Juetteman, T. et al. Ensembl regulation resources. Database (2015) Vol. 2015: article ID bav119; doi:10.1093/database/bav119
Resumo: New experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl project collects and maintains the Ensembl regulation data resources on epigenetic marks, transcription factor binding and DNA methylation for human and mouse, as well as microarray probe mappings and annotations for a variety of chordate genomes. From this data, we produce a functional annotation of the regulatory elements along the human and mouse genomes with plans to expand to other species as data becomes available. Starting from well-studied cell lines, we will progressively expand our library of measurements to a greater variety of samples. Ensembl's regulation resources provide a central and easy-to-query repository for reference epigenomes. As with all Ensembl data, it is freely available at http://www.ensembl.org, from the Perl and REST APIs and from the public Ensembl MySQL database server at ensembldb.ensembl.org.Database URL: http://www.ensembl.org.
Peer review: yes
URI: http://hdl.handle.net/10400.7/589
DOI: 10.1093/database/bav119
Versão do Editor: http://database.oxfordjournals.org/content/2016/bav119.long
Aparece nas colecções:BCBU- Artigos

Ficheiros deste registo:
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Database-2016-Zerbino-database_bav119.pdfartigo principal1,98 MBAdobe PDFVer/Abrir
Supplemental_Methods.docxmaterial suplementar 1535,52 kBMicrosoft Word XMLVer/Abrir

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