Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/615
Título: Genetics. Sowing the seeds of centromeres.
Autor: Jansen, L. E. T.
Palavras-chave: Animals
Centromere
Drosophila
Histones
Data: 20-Jan-2012
Editora: American Association for the Advancement of Science
Citação: Jansen, L. E. T. (2012). Genetics. Sowing the seeds of centromeres. Science, 335(6066), 299–300.
Resumo: The centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior?
Peer review: yes
URI: http://hdl.handle.net/10400.7/615
DOI: 10.1126/science.1218162
Versão do Editor: http://science.sciencemag.org/content/335/6066/299.full
Aparece nas colecções:EM - Artigos

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