Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/814
Título: Changes in Expression of the CLOCK Gene in Obstructive Sleep Apnea Syndrome Patients Are Not Reverted by Continuous Positive Airway Pressure Treatment
Autor: Moreira, Susana
Rodrigues, Raquel
Barros, André B.
Pejanovic, Nadja
Neves-Costa, Ana
Pedroso, Dora
Pereira, Cláudia
Fernandes, Dina
Rodrigues, João Valença
Barbara, Cristina
Moita, Luís Ferreira
Palavras-chave: obstructive sleep apnea syndrome
clock genes
continuous positive airway pressure
slow wave sleep
Metabolic Syndrome
Circadian Rhythms
Data: 6-Nov-2017
Editora: Frontiers Media
Citação: Moreira S, Rodrigues R, Barros AB, Pejanovic N, Neves-Costa A, Pedroso D, Pereira C, Fernandes D, Rodrigues JV, Barbara C and Moita LF (2017) Changes in Expression of the CLOCK Gene in Obstructive Sleep Apnea Syndrome Patients Are Not Reverted by Continuous Positive Airway Pressure Treatment. Front. Med. 4:187. doi: 10.3389/fmed.2017.00187
Resumo: Metabolic syndrome and cardiovascular disease are strongly associated with obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal circadian physiological functions, including metabolic pathways. Because core clock genes are known to be modulated by sleep/vigilance cycles, we asked whether the expression level of mRNA coding for clock genes is altered in non-treated OSAS patients and if it can be corrected by standard continuous positive airway pressure (CPAP) treatment.
Descrição: This deposit is composed by the main article plus the supplementary materials of the publication.
Peer review: yes
URI: http://hdl.handle.net/10400.7/814
DOI: 10.3389/fmed.2017.00187
Versão do Editor: https://www.frontiersin.org/articles/10.3389/fmed.2017.00187/full
Aparece nas colecções:III- Artigos

Ficheiros deste registo:
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Moreira_Front.Med.(2017).pdfmain article138,24 kBAdobe PDFVer/Abrir
Moreira_Front.Med.(2017)_SM.pdfsupplementary materials199,21 kBAdobe PDFVer/Abrir


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