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Title: Alternative Splicing Control of Abiotic Stress Responses
Author: Laloum, Tom
Martín, Guiomar
Duque, Paula
Keywords: abiotic stress
abscisic acid (ABA)
alternative splicing
post-transcriptional regulation
RNA-binding protein
Issue Date: Feb-2018
Publisher: Elsevier
Citation: Laloum,T, Martin, G., Duque, P. (2018). Alternative Splicing Control of Abiotic Stress Responses. Trends in Plant Science. 23(2): 140 - 150.
Abstract: Alternative splicing, which generates multiple transcripts from the same gene, is an important modulator of gene expression that can increase proteome diversity and regulate mRNA levels. In plants, this post-transcriptional mechanism is markedly induced in response to environmental stress, and recent studies have identified alternative splicing events that allow rapid adjustment of the abundance and function of key stress-response components. In agreement, plant mutants defective in splicing factors are severely impaired in their response to abiotic stress. Notably, mounting evidence indicates that alternative splicing regulates stress responses largely by targeting the abscisic acid (ABA) pathway. We review here current understanding of post-transcriptional control of plant stress tolerance via alternative splicing and discuss research challenges for the near future.
Description: The deposited article is a post-print version and has been submitted to peer review.
This publication hasn't any creative commons license associated.
This deposit is composed by the main article, and it hasn't any supplementary materials associated.
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Peer review: yes
DOI: 10.1016/j.tplants.2017.09.019
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Appears in Collections:PMB - Artigos

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