Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/869
Título: Noncanonical Biogenesis of Centrioles and Basal Bodies
Autor: Nabais, Catarina
Pereira, Sónia Gomes
Bettencourt-Dias, Mónica
Palavras-chave: Centrioles
Basal Bodies
Data: Abr-2018
Editora: Cold Spring Harbor Laboratory Press
Citação: SYMPOSIUM - Early Release Article: Noncanonical Biogenesis of Centrioles and Basal Bodies Catarina Nabais, Sónia Gomes Pereira, and Mónica Bettencourt-Dias Cold Spring Harb Symp Quant Biol 034694Published in Advance April 23, 2018, doi:10.1101/sqb.2017.82.034694
Resumo: Centrioles and basal bodies (CBBs) organize centrosomes and cilia within eukaryotic cells. These organelles are composed of microtubules and hundreds of proteins performing multiple functions such as signaling, cytoskeleton remodeling, and cell motility. The CBB is present in all branches of the eukaryotic tree of life and, despite its ultrastructural and protein conservation, there is diversity in its function, occurrence (i.e., presence/absence), and modes of biogenesis across species. In this review, we provide an overview of the multiple pathways through which CBBs are formed in nature, with a special focus on the less studied, noncanonical ways. Despite the differences among each mechanism herein presented, we highlighted some of their common principles. These principles, governing different steps of biogenesis, ensure that CBBs may perform a multitude of functions in a huge diversity of organisms but yet retained their robustness in structure throughout evolution.
Descrição: The deposited article is a pre-print version.
The deposited article version is the Epub Ahead of Print version of the article, posted online 23 April 2018, provided by Cold Spring Harbor Laboratory Press. It hasn't peer-review.
This deposit is composed by the main article, and it hasn't any supplementary materials associated.
Peer review: no
URI: http://hdl.handle.net/10400.7/869
DOI: 10.1101/sqb.2017.82.034694
Versão do Editor: http://symposium.cshlp.org/content/early/2018/04/21/sqb.2017.82.034694.abstract
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