Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/894
Título: In search of the Goldilocks zone for hybrid speciation
Autor: Blanckaert, Alexandre
Bank, Claudia
Palavras-chave: Hybrid specification
Haplotypes
Genetic Loci
Alleles
Population Size
Natural Selection
Epistasis
Population genetics
Data: 7-Set-2018
Citação: Citation: Blanckaert A, Bank C (2018) In search of the Goldilocks zone for hybrid speciation. PLoS Genet 14(9): e1007613. https://doi.org/10.1371/ journal.pgen.1007613
Resumo: Hybridization has recently gained considerable interest both as a unique opportunity for observing speciation mechanisms and as a potential engine for speciation. The latter remains a controversial topic. It was recently hypothesized that the reciprocal sorting of genetic incompatibilities from parental species could result in hybrid speciation, when the hybrid population maintains a mixed combination of the parental incompatibilities that prevents further gene exchange with both parental populations. However, the specifics of the purging/sorting process of multiple incompatibilities have not been examined theoretically. We here investigate the allele-frequency dynamics of an isolated hybrid population that results from a single hybridization event. Using models of two or four loci, we investigate the fate of one or two genetic incompatibilities of the Dobzhansky-Muller type (DMIs). We study how various parameters affect both the sorting/purging of the DMIs and the probability of observing hybrid speciation by reciprocal sorting. We find that the probability of hybrid speciation is strongly dependent on the linkage architecture (i.e. the order and recombination rate between loci along chromosomes), the population size of the hybrid population, and the initial relative contributions of the parental populations to the hybrid population. We identify a Goldilocks zone for specific linkage architectures and intermediate recombination rates, in which hybrid speciation becomes highly probable. Whereas an equal contribution of parental populations to the hybrid population maximizes the hybrid speciation probability in the Goldilocks zone, other linkage architectures yield unintuitive asymmetric maxima. We provide an explanation for this pattern, and discuss our results both with respect to the best conditions for observing hybrid speciation in nature and their implications regarding patterns of introgression in hybrid zones.
Descrição: This deposit is composed by the main article plus the supplementary materials of the publication.
The supplementary materials can also be accessed through the following link: https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007613#sec021
Peer review: yes
URI: http://hdl.handle.net/10400.7/894
DOI: 10.1371/journal.pgen.1007613
Versão do Editor: https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007613
Aparece nas colecções:ED- Artigos

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
Blanckaert_Plos.Genet._(2018).pdfmain article8,58 MBAdobe PDFVer/Abrir
Blanckaert_Plos.Genet._(2018)_SM.pdfsupplementary materials5,67 MBAdobe PDFVer/Abrir


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