Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/91
Título: Nonequilibrium model for estimating parameters of deleterious mutations
Autor: Gordo, I.
Dionisio, F.
Palavras-chave: Evolution
Genetic Variation/genetics
Genetics, Population/methods
Models, Genetic
Population Dynamics
Selection, Genetic
Data: 18-Mar-2005
Editora: American Physical Society
Citação: Gordo, I., Dionisio, F. (2005). Nonequilibrium model for estimating parameters of deleterious mutations. Phys. Rev. E. 71(3), 031907
Resumo: Deleterious mutations are of extreme evolutionary importance because, even though they are eliminated by natural selection, their continuous pressure creates a pool of variability in natural populations. They are of potential relevance for the existence of several features in evolution, such as sexual reproduction, and pose a risk to small asexual populations. Despite their extreme importance, the deleterious mutation rate and the effects of each mutation on fitness are poorly known quantities. Here we analyze a simple model that can be applied to simple experiments, in microorganisms, aiming at the quantification of these values.
URI: http://hdl.handle.net/10400.7/91
DOI: 10.1103/PhysRevE.71.031907
ISSN: ISSN: 1539-3755
Aparece nas colecções:EB - Articles

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