Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.7/92
Título: Scaling, genetic drift and clonal interference in the extinction pattern of asexual populations
Autor: Rosas, A.
Gordo, I.
Campos, P.R.A.
Palavras-chave: Extinction, Psychological
Genetic Drift
Genetics, Population
Reproduction, Asexual
Data: 5-Jul-2005
Editora: American Physical Society
Citação: Rosas, A., I.Gordo and P.R.A. Campos (2005) Scaling, genetic drift and clonal interference in the extinction pattern of asexual populations. Phys.Rev. E 72, 012901
Resumo: We investigate the dynamics of loss of favorable mutations in an asexual haploid population. In the current work, we consider homogeneous as well as spatially structured population models. We focus our analysis on statistical measurements of the probability distribution of the maximum population size N(sb) achieved by those mutations that have not reached fixation. Our results show a crossover behavior which demonstrates the occurrence of two evolutionary regimes. In the first regime, which takes place for small N(sb) , the probability distribution is described by a power law with characteristic exponent theta(d) =1.8 +/- 0.01. This power law is not influenced by the rate of beneficial mutations. The second regime, which occurs for intermediate to large values of N(sb), has a characteristic exponent theta(c) which increases as the rate of beneficial mutations grows. These results establish where genetic drift and clonal interference become the main underlying mechanism in the extinction of advantageous mutations.
URI: http://hdl.handle.net/10400.7/92
DOI: 10.1103/PhysRevE.72.012901
ISSN: 1744-9561
Versão do Editor: https://www.ncbi.nlm.nih.gov/pubmed/16090018
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