Please use this identifier to cite or link to this item: http://hdl.handle.net/10400.7/216
Title: Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
Author: Fesel, C.
Goulart, L.F.
Neto, A.S.
Coelho, A.
Fontes, C.J.F.
Braga, E.M.
Vaz, N.M.
Keywords: Immunity, Innate/immunology
Immunoglobulin G/blood
Immunoglobulin G/immunology
Malaria, Falciparum/epidemiology
Malaria, Falciparum/immunology
Malaria, Vivax/epidemiology
Malaria, Vivax/immunology
Escherichia coli Proteins/immunology
Issue Date: Jan-2005
Publisher: Biomed Central
Citation: Fesel, C., L. F. Goulart, A. S. Neto, A. Coelho, C. J. F. Fontes, E. M. Braga and N. M. Vaz (2005). "Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection." Malaria Journal 4:5
Abstract: The observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction.
Peer review: yes
URI: http://hdl.handle.net/10400.7/216
http://dx.doi.org/10.1186/1475-2875-4-5
ISSN: 1475-2875
Publisher Version: http://www.malariajournal.com/content/4/1/5
Appears in Collections:LAIR articles

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