Remy, EstelleBaster, PawelFriml, JiříDuque, Paula2016-04-262016-04-262013-07-10Estelle Remy, Pawel Baster, Ji ř í Friml & Paula Duque (2013) ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip, Plant Signaling & Behavior, 8:10, e25688, DOI: 10.4161/psb.25688http://hdl.handle.net/10400.7/587Cell-to-cell directional flow of the phytohormone auxin is primarily established by polar localization of the PIN auxin transporters, a process tightly regulated at multiple levels by auxin itself. We recently reported that, in the context of strong auxin flows, activity of the vacuolar ZIFL1.1 transporter is required for fine-tuning of polar auxin transport rates in the Arabidopsis root. In particular, ZIFL1.1 function protects plasma-membrane stability of the PIN 2 carrier in epidermal root tip cells under conditions normally triggering PIN 2 degradation. Here, we show that ZIFL1.1 activity at the root tip also promotes PIN 1 plasma-membrane abundance in central cylinder cells, thus supporting the notion that ZIFL1.1 acts as a general positive modulator of polar auxin transport in roots.engArabidopsis thalianaMajor Facilitator SuperfamilyPIN transporterspolar auxin transportroot developmentjournal article10.4161/psb.25688