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Ensembl regulation resources

2015-11-24Journal article Open access
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dc.contributor.authorZerbino, Daniel R.
dc.contributor.authorJohnson, Nathan
dc.contributor.authorJuetteman, Thomas
dc.contributor.authorSheppard, Dan
dc.contributor.authorWilder, Steven P.
dc.contributor.authorLavidas, Ilias
dc.contributor.authorNuhn, Michael
dc.contributor.authorPerry, Emily
dc.contributor.authorRaffaillac-Desfosses, Quentin
dc.contributor.authorSobral, Daniel
dc.contributor.authorKeefe, Damian
dc.contributor.authorGräf, Stefan
dc.contributor.authorAhmed, Ikhlak
dc.contributor.authorKinsella, Rhoda
dc.contributor.authorPritchard, Bethan
dc.contributor.authorBrent, Simon
dc.contributor.authorAmode, Ridwan
dc.contributor.authorParker, Anne
dc.contributor.authorTrevanion, Steven
dc.contributor.authorBirney, Ewan
dc.contributor.authorDunham, Ian
dc.contributor.authorFlicek, Paul
dc.date.accessioned2016-04-27T17:12:27Z
dc.date.available2016-04-27T17:12:27Z
dc.date.issued2015-11-24
dc.description.abstractNew experimental techniques in epigenomics allow researchers to assay a diversity of highly dynamic features such as histone marks, DNA modifications or chromatin structure. The study of their fluctuations should provide insights into gene expression regulation, cell differentiation and disease. The Ensembl project collects and maintains the Ensembl regulation data resources on epigenetic marks, transcription factor binding and DNA methylation for human and mouse, as well as microarray probe mappings and annotations for a variety of chordate genomes. From this data, we produce a functional annotation of the regulatory elements along the human and mouse genomes with plans to expand to other species as data becomes available. Starting from well-studied cell lines, we will progressively expand our library of measurements to a greater variety of samples. Ensembl's regulation resources provide a central and easy-to-query repository for reference epigenomes. As with all Ensembl data, it is freely available at http://www.ensembl.org, from the Perl and REST APIs and from the public Ensembl MySQL database server at ensembldb.ensembl.org.Database URL: http://www.ensembl.org.pt_PT
dc.description.sponsorshipWellcome Trust grant: (WT098051); National Human Genome Research Institute grants: (U41HG007234, 1U01 HG004695); Biotechnology and Biological Sciences Research Council grant: (BB/L024225/1); European Molecular Biology Laboratory; European Union’s Seventh Framework Programme; European Research Council.pt_PT
dc.identifier.citationZerbino, D.R., Johnson, N., Juetteman, T. et al. Ensembl regulation resources. Database (2015) Vol. 2015: article ID bav119; doi:10.1093/database/bav119pt_PT
dc.identifier.doi10.1093/database/bav119pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.7/589
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relationA BLUEPRINT of Haematopoietic Epigenomes
dc.relationCis-regulatory logic of the transcriptional control in neural stem cells
dc.relationFrom Sequence to Consequence - Tools for the Exploitation of Livestock Genomes
dc.relationEuropean large-scale functional genomics in the rat for translational research
dc.relationHealth and Environmental Risks: Organisation, Integration and Cross-fertilisation of Scientific Knowledge
dc.relationServing Life-science Information for the Next Generation
dc.relation.publisherversionhttp://database.oxfordjournals.org/content/2016/bav119.longpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectGenomept_PT
dc.subjectDNApt_PT
dc.titleEnsembl regulation resourcespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleA BLUEPRINT of Haematopoietic Epigenomes
oaire.awardTitleCis-regulatory logic of the transcriptional control in neural stem cells
oaire.awardTitleFrom Sequence to Consequence - Tools for the Exploitation of Livestock Genomes
oaire.awardTitleEuropean large-scale functional genomics in the rat for translational research
oaire.awardTitleHealth and Environmental Risks: Organisation, Integration and Cross-fertilisation of Scientific Knowledge
oaire.awardTitleServing Life-science Information for the Next Generation
oaire.awardURIinfo:eu-repo/grantAgreement/WT/095908
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/282510/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/223210/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/222664/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/241504/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/282896/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/226073/EU
oaire.citation.endPage13pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleDatabasept_PT
oaire.citation.volume2015pt_PT
oaire.fundingStream095908
oaire.fundingStreamFP7
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project.funder.identifierhttp://doi.org/10.13039/100010269
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project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameWellcome Trust
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isProjectOfPublication.latestForDiscovery59a32730-1596-4a5d-b722-824c94e98ee5

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