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Evolution of commensal bacteria in the intestinal tract of mice

2017-08Journal article Open access
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dc.contributor.authorSousa, Ana
dc.contributor.authorFrazão, Nelson
dc.contributor.authorRamiro, Ricardo S
dc.contributor.authorGordo, Isabel
dc.date.accessioned2018-05-18T14:32:13Z
dc.date.available2018-08-01T00:30:08Z
dc.date.issued2017-08
dc.descriptionThe deposited article is a post-print version and has been submitted to peer review.pt_PT
dc.descriptionThis deposit is composed by the main article, and it hasn't any supplementary materials associated.pt_PT
dc.descriptionThis publication hasn't any creative commons license associated.pt_PT
dc.description.abstractHundreds of different bacterial species inhabit our intestines and contribute to our health status, with significant loss of species diversity typically observed in disease conditions. Within each microbial species a great deal of diversity is hidden and such intra-specific variation is also key to the proper homeostasis between the host and its microbial inhabitants. Indeed, it is at this level that new mechanisms of antibiotic resistance emerge and pathogenic characteristics evolve. Yet, our knowledge on intra-species variation in the gut is still limited and an understanding of the evolutionary mechanisms acting on it is extremely reduced. Here we review recent work that has begun to reveal that adaptation of commensal bacteria to the mammalian intestine may be fast and highly repeatable, and that the time scales of evolutionary and ecological change can be very similar in these ecosystems.pt_PT
dc.description.sponsorshipDeutsche Forschungsgemeinschaft Grant SFB 680 and the Portuguese Science and Technology Foundation FCT (SFRH/BPD/111725/2015 and UID/BIM/04501/2013 support to AS, SFRH/BPD/110750/2015 support to NF).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAna Sousa, Nelson Frazão, Ricardo S Ramiro, Isabel Gordo, Evolution of commensal bacteria in the intestinal tract of mice, Current Opinion in Microbiology, Volume 38, 2017, Pages 114-121, ISSN 1369-5274, https://doi.org/10.1016/j.mib.2017.05.007. (http://www.sciencedirect.com/science/article/pii/S1369527416301527)pt_PT
dc.identifier.doi10.1016/j.mib.2017.05.007pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.7/872
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationSFB 680pt_PT
dc.relationRapid evolution of decreased mutation rates in hypermutator bacteria
dc.relationImpact of host-to-host bacterial transmission on gut microbiota
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1369527416301527?via%3Dihubpt_PT
dc.subjectCommensal bacteriapt_PT
dc.subjectmicept_PT
dc.subjectgut microbiotapt_PT
dc.subjectEvolutionary changept_PT
dc.subjectMutationpt_PT
dc.subjectBacterial Speciespt_PT
dc.titleEvolution of commensal bacteria in the intestinal tract of micept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleRapid evolution of decreased mutation rates in hypermutator bacteria
oaire.awardTitleImpact of host-to-host bacterial transmission on gut microbiota
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F111725%2F2015/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FBIM%2F04501%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F110750%2F2015/PT
oaire.citation.endPage121pt_PT
oaire.citation.startPage114pt_PT
oaire.citation.titleCurrent Opinion in Microbiologypt_PT
oaire.citation.volume38pt_PT
oaire.fundingStream5876
oaire.fundingStreamOE
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctThe deposited article has 12 months of embargo period in terms of access, because of the journal's policies and the publisher's copyright policy, which require a period of 12 months of embargo after the released date of the publication.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication4eb7c1db-8038-44ea-b6e1-186239c25c4a
relation.isProjectOfPublication40f8b88b-8687-43bd-9eec-082546220516
relation.isProjectOfPublication06a1b8c7-8307-4716-a12c-05dd6eca5db7
relation.isProjectOfPublication.latestForDiscovery06a1b8c7-8307-4716-a12c-05dd6eca5db7

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