The role of juvenile hormone and insulin/TOR signaling in the growth of Manduca sexta

Hatem, Nicole E.; Wang, Zhou; Nave, Keelin B.; Koyama, Takashi; Suzuki, Yuichiro

http://hdl.handle.net/10400.7/398

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Abstract(s)

In many insect species, fitness trade-offs exist between maximizing body size and developmental speed. Understanding how various species evolve different life history strategies requires knowledge of the physiological mechanisms underlying the regulation of body size and developmental timing. Here the roles of juvenile hormone (JH) and insulin/target of rapamycin (TOR) signaling in the regulation of the final body size were examined in the tobacco hornworm, Manduca sexta.

Keywords

Developmental timing Critical weight Life history trade-offs Manduca sexta Drosophila melanogaster Metamorphosis Insulin/TOR signaling Juvenile hormone Prothoracic gland Molt timer