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Neural representation of behavioral outcomes in the orbitofrontal cortex

dc.contributor.authorMainen, ZF
dc.contributor.authorKepecs, A
dc.date.accessioned2010-08-05T09:55:34Z
dc.date.available2010-08-05T09:55:34Z
dc.date.issued2009-02
dc.description.abstractThe orbitofrontal cortex (OFC) is important in processing rewards and other behavioral outcomes. Here, we review from a computational perspective recent progress in understanding this complex function. OFC neurons appear to represent abstract outcome values, which may facilitate the comparison of options, as well as concrete outcome attributes, such as flavor or location, which may enable predictive cues to access current outcome values in the face of dynamic modulation by internal state, context and learning. OFC can use reinforcement learning to generate outcome predictions; it can also generate outcome predictions using other mechanisms, including the evaluation of decision confidence or uncertainty. OFC neurons encode not only the mean expected outcome but also the variance, consistent with the idea that OFC uses a probabilistic population code to represent outcomes. We suggest that further attention to the nature of its representations and algorithms will be critical to further elucidating OFC function.pt
dc.identifier.citationMainem, ZF., Kepecs, A. (2009). “Neural representations of behavioral outcomes in the orbitofrontal cortex”.Current Opinion in Neurobiology. 19 (1):84-91pt
dc.identifier.issn0959-4388
dc.identifier.urihttp://hdl.handle.net/10400.7/144
dc.language.isoengpt
dc.publisherCurrent Biologypt
dc.subjectDECISION-MAKINGpt
dc.subjectPREFRONTAL CORTEXpt
dc.subjectMATCHING BEHAVIORpt
dc.subjectNEURONAL-ACTIVITYpt
dc.subjectPOPULATION CODESpt
dc.subjectENCODES RESPONSEpt
dc.titleNeural representation of behavioral outcomes in the orbitofrontal cortexpt
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceEnglandpt
oaire.citation.endPage91pt
oaire.citation.startPage84pt
oaire.citation.titleCurrent Opinion in Neurobiologypt
rcaap.rightsopenAccesspt
rcaap.typearticlept

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