Publication
Asymptomatic Plasmodium falciparum infection in children is associated with increased auto-antibody production, high IL-10 plasma levels and antibodies to merozoite surface protein 3
| dc.contributor.author | Guiyedi, Vincent | |
| dc.contributor.author | Bécavin, Christophe | |
| dc.contributor.author | Herbert, Fabien | |
| dc.contributor.author | Gray, Julian | |
| dc.contributor.author | Cazenave, Pierre-André | |
| dc.contributor.author | Kombila, Maryvonne | |
| dc.contributor.author | Crisanti, Andrea | |
| dc.contributor.author | Fesel, Constantin | |
| dc.contributor.author | Pied, Sylviane | |
| dc.date.accessioned | 2015-10-20T14:54:06Z | |
| dc.date.available | 2015-10-20T14:54:06Z | |
| dc.date.issued | 2015-04-16 | |
| dc.description.abstract | Mechanisms of acquired protection to malaria in asymptomatic Plasmodium falciparum carriers are only partially understood. Among them, the role plays by the self-reactive antibodies has not been clarified yet. In this study, the relationship between repertoires of circulating self-reactive and parasite-specific immunoglobulin G (IgG), their correlation with cytokine levels, and their association with protection against malaria was investigated in asymptomatic Plasmodium falciparum-infected Gabonese children. | pt_PT |
| dc.description.sponsorship | Centre National de la Recherche Scientifique-Laboratoires Européen Associés ‘Génétique et développement de la tolérance naturelle’ programme, French Ministry of Research and LabEx Parafrap - PAL+ programme: (ANR-11-LABX-0024), FCT fellowships: postdoctoral fellowship and visiting scientist fellowship, Agence Universitaire de la Francophonie (AUF) fellowship, Agence Nationale de Recherches sur le SIDA et les hépatites virales (ANRS) fellowship. | pt_PT |
| dc.identifier | 10.1186/s12936-015-0658-7 | |
| dc.identifier.doi | 10.1186/s12936-015-0658-7 | |
| dc.identifier.uri | http://hdl.handle.net/10400.7/413 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | BioMed Central | pt_PT |
| dc.relation.publisherversion | http://www.malariajournal.com/content/14/1/162 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Auto-antibody | pt_PT |
| dc.subject | Antibody response | pt_PT |
| dc.subject | Plasmodium falciparum | pt_PT |
| dc.subject | Malaria | pt_PT |
| dc.subject | Cytokines | pt_PT |
| dc.title | Asymptomatic Plasmodium falciparum infection in children is associated with increased auto-antibody production, high IL-10 plasma levels and antibodies to merozoite surface protein 3 | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 11 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | Malaria Journal | pt_PT |
| oaire.citation.volume | 14 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |