In search of the Goldilocks zone for hybrid speciation

Blanckaert, Alexandre; Bank, Claudia

Publication

In search of the Goldilocks zone for hybrid speciation

2018-09-07Journal article

dc.contributor.author	Blanckaert, Alexandre
dc.contributor.author	Bank, Claudia
dc.date.accessioned	2018-09-25T10:54:01Z
dc.date.available	2018-09-25T10:54:01Z
dc.date.issued	2018-09-07
dc.description	This deposit is composed by the main article plus the supplementary materials of the publication.	pt_PT
dc.description	The supplementary materials can also be accessed through the following link: https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007613#sec021	pt_PT
dc.description.abstract	Hybridization has recently gained considerable interest both as a unique opportunity for observing speciation mechanisms and as a potential engine for speciation. The latter remains a controversial topic. It was recently hypothesized that the reciprocal sorting of genetic incompatibilities from parental species could result in hybrid speciation, when the hybrid population maintains a mixed combination of the parental incompatibilities that prevents further gene exchange with both parental populations. However, the specifics of the purging/sorting process of multiple incompatibilities have not been examined theoretically. We here investigate the allele-frequency dynamics of an isolated hybrid population that results from a single hybridization event. Using models of two or four loci, we investigate the fate of one or two genetic incompatibilities of the Dobzhansky-Muller type (DMIs). We study how various parameters affect both the sorting/purging of the DMIs and the probability of observing hybrid speciation by reciprocal sorting. We find that the probability of hybrid speciation is strongly dependent on the linkage architecture (i.e. the order and recombination rate between loci along chromosomes), the population size of the hybrid population, and the initial relative contributions of the parental populations to the hybrid population. We identify a Goldilocks zone for specific linkage architectures and intermediate recombination rates, in which hybrid speciation becomes highly probable. Whereas an equal contribution of parental populations to the hybrid population maximizes the hybrid speciation probability in the Goldilocks zone, other linkage architectures yield unintuitive asymmetric maxima. We provide an explanation for this pattern, and discuss our results both with respect to the best conditions for observing hybrid speciation in nature and their implications regarding patterns of introgression in hybrid zones.	pt_PT
dc.description.sponsorship	This research was supported by the Fundação Calouste Gulbenkian. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Citation: Blanckaert A, Bank C (2018) In search of the Goldilocks zone for hybrid speciation. PLoS Genet 14(9): e1007613. https://doi.org/10.1371/ journal.pgen.1007613	pt_PT
dc.identifier.doi	10.1371/journal.pgen.1007613	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.7/894
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.relation	This research was supported by the Fundação Calouste Gulbenkian. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.	pt_PT
dc.relation.publisherversion	https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007613	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Hybrid specification	pt_PT
dc.subject	Haplotypes	pt_PT
dc.subject	Genetic Loci	pt_PT
dc.subject	Alleles	pt_PT
dc.subject	Population Size	pt_PT
dc.subject	Natural Selection	pt_PT
dc.subject	Epistasis	pt_PT
dc.subject	Population genetics	pt_PT
dc.title	In search of the Goldilocks zone for hybrid speciation	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.endPage	23	pt_PT
oaire.citation.issue	9	pt_PT
oaire.citation.startPage	1	pt_PT
oaire.citation.title	PLoS Genetics	pt_PT
oaire.citation.volume	14	pt_PT
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT