INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community

Meehan, T.F.; Demengeot, Jocelyne; 44 colaborators, Infrafrontier Consortium

Publication

INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community

2014-11-03Journal article

dc.contributor.author	Meehan, T.F.
dc.contributor.author	Demengeot, Jocelyne
dc.contributor.author	44 colaborators, Infrafrontier Consortium
dc.date.accessioned	2015-10-20T16:28:21Z
dc.date.available	2015-10-20T16:28:21Z
dc.date.issued	2014-11-03
dc.description	This deposit is composed by a publication in which the IGC' authors have had the role of collaboration (it's a collaboration publication). This type of deposit in ARCA is in restrictedAccess (it can't be in open access to the public), and could only be accessed by two ways: either by requesting a legal copy to the author (the email contact present in this deposit) or by visiting the following link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383977/	pt_PT
dc.description.abstract	The laboratory mouse is a key model organism to investigate mechanism and therapeutics of human disease. The number of targeted genetic mouse models of disease is growing rapidly due to high-throughput production strategies employed by the International Mouse Phenotyping Consortium (IMPC) and the development of new, more efficient genome engineering techniques such as CRISPR based systems. We have previously described the European Mouse Mutant Archive (EMMA) resource and how this international infrastructure provides archiving and distribution worldwide for mutant mouse strains. EMMA has since evolved into INFRAFRONTIER (http://www.infrafrontier.eu), the pan-European research infrastructure for the systemic phenotyping, archiving and distribution of mouse disease models. Here we describe new features including improved search for mouse strains, support for new embryonic stem cell resources, access to training materials via a comprehensive knowledgebase and the promotion of innovative analytical and diagnostic techniques.	pt_PT
dc.description.sponsorship	European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI).	pt_PT
dc.identifier	10.1093/nar/gku1193
dc.identifier.citation	The 2015 Nucleic Acids Research Database Issue and Molecular Biology Database Collection Nucleic Acids Res (2015) 43 (D1): D1-D5	pt_PT
dc.identifier.doi	10.1093/nar/gku1193
dc.identifier.doi	10.1093/nar/gku1193
dc.identifier.doi	10.1093/nar/gku1193
dc.identifier.uri	http://hdl.handle.net/10400.7/416
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Oxford University Press	pt_PT
dc.relation	Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation
dc.relation.publisherversion	https://academic.oup.com/nar/article/43/D1/D1171/2439071	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.title	INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.awardTitle	Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation
oaire.awardURI	info:eu-repo/grantAgreement/EC/FP7/312325/EU
oaire.citation.endPage	D1175	pt_PT
oaire.citation.startPage	D1171	pt_PT
oaire.citation.title	Nucleic Acids Research	pt_PT
oaire.citation.volume	43	pt_PT
oaire.fundingStream	FP7
project.funder.identifier	http://doi.org/10.13039/501100008530
project.funder.name	European Commission
rcaap.rights	restrictedAccess	pt_PT
rcaap.type	article	pt_PT
relation.isProjectOfPublication	c8305e81-2896-48ab-8ae3-470d257dfdd0
relation.isProjectOfPublication.latestForDiscovery	c8305e81-2896-48ab-8ae3-470d257dfdd0