ORG- Artigos

Our group focuses on the study of the cellular and molecular mechanisms controlling limb development and fin regeneration. We are trying to understand how the main signalling centre in limb development, the Apical Ectodermal Ridge (AER), is established and maintained through development and how different molecules, namely those related to stemness, are involved in these processes. Also, we have developed a line of research directed to depict how ion dynamics can control limb development, digit differentiation and fin regeneration. In these studies we use the chicken and zebrafish embryos as well as adult zebrafish as animal models.