Cell Cycle Regulation

Our research focuses on cell cycle progression and the cytoskeleton in normal development and disease. We are particularly interested in the role played by microtubule organizing structures, such as the centrosome, cilia and flagella. The centrosome is the major microtubule organizer in animal cells, and is very often abnormal in cancer. Cilia and flagella are cellular projections which are indispensable in a variety of cellular and developmental processes including cell motility, propagation of morphogenic signals and sensory reception.