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Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti

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The TolC protein from Sinorhizobium meliloti has previously been demonstrated to be required for establishing successful biological nitrogen fixation symbiosis with Medicago sativa. It is also needed in protein and exopolysaccharide secretion and for protection against osmotic and oxidative stresses. Here, the transcriptional profile of free-living S. meliloti 1021 tolC mutant is described as a step toward understanding its role in the physiology of the cell.

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Santos, Mário R, Cosme, Ana M, Becker Jorg D, Medeiros, João MC, Mata, Márcia F, Moreira, leonilde M. (2010). “Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti” BMC Microbiology 10:180

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