Publication
Nonequilibrium model for estimating parameters of deleterious mutations
| dc.contributor.author | Gordo, I. | |
| dc.contributor.author | Dionisio, F. | |
| dc.date.accessioned | 2010-03-25T16:03:24Z | |
| dc.date.available | 2010-03-25T16:03:24Z | |
| dc.date.issued | 2005-03-18 | |
| dc.description.abstract | Deleterious mutations are of extreme evolutionary importance because, even though they are eliminated by natural selection, their continuous pressure creates a pool of variability in natural populations. They are of potential relevance for the existence of several features in evolution, such as sexual reproduction, and pose a risk to small asexual populations. Despite their extreme importance, the deleterious mutation rate and the effects of each mutation on fitness are poorly known quantities. Here we analyze a simple model that can be applied to simple experiments, in microorganisms, aiming at the quantification of these values. | pt_PT |
| dc.identifier.citation | Gordo, I., Dionisio, F. (2005). Nonequilibrium model for estimating parameters of deleterious mutations. Phys. Rev. E. 71(3), 031907 | |
| dc.identifier.doi | 10.1103/PhysRevE.71.031907 | |
| dc.identifier.issn | ISSN: 1539-3755 | |
| dc.identifier.uri | http://hdl.handle.net/10400.7/91 | |
| dc.language.iso | eng | pt |
| dc.publisher | American Physical Society | pt |
| dc.subject | Evolution | pt |
| dc.subject | Genetic Variation/genetics | pt |
| dc.subject | Genetics, Population/methods | pt |
| dc.subject | Models, Genetic | pt |
| dc.subject | Mutation/genetics | pt |
| dc.subject | Population Dynamics | pt |
| dc.subject | Selection, Genetic | pt |
| dc.title | Nonequilibrium model for estimating parameters of deleterious mutations | pt |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 031907-4 | pt |
| oaire.citation.startPage | 031907-1 | pt |
| oaire.citation.title | Physical Review | pt |
| rcaap.rights | openAccess | pt |
| rcaap.type | article | pt |
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