Publication
Self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in Gabonese children
| dc.contributor.author | Guiyedi, V. | |
| dc.contributor.author | Chanseaud, Y. | |
| dc.contributor.author | Fesel, C. | |
| dc.contributor.author | Snounou, G. | |
| dc.contributor.author | Rousselle, J.C. | |
| dc.contributor.author | Lim, P. | |
| dc.contributor.author | Koko, J. | |
| dc.contributor.author | Namane, A. | |
| dc.contributor.author | Cazenave, P.A. | |
| dc.contributor.author | Kombila, M. | |
| dc.contributor.author | Pied, S. | |
| dc.date.accessioned | 2011-05-18T16:29:42Z | |
| dc.date.available | 2011-05-18T16:29:42Z | |
| dc.date.issued | 2007-04 | |
| dc.description.abstract | Hypergammaglobulinemia and polyclonal B-cell activation commonly occur in Plasmodium sp. infections. Some of the antibodies produced recognize self-components and are correlated with disease severity in P. falciparum malaria. However, it is not known whether some self-reactive antibodies produced during P. falciparum infection contribute to the events leading to cerebral malaria (CM). We show here a correlation between self-antibody responses to a human brain protein and high levels of circulating TNF alpha (TNFα), with the manifestation of CM in Gabonese children | por |
| dc.identifier.citation | Guiyedi, V, Chanseaud, Y., Fesel C., Snounou G., Rousselle J.-C., Lim P., Koko J., Namane A., Cazenave P.-A., Kombila M., Pied S. (2007) “Self-reactivities to the non-erythroid Alpha Spectrin correlate with cerebral malaria in Gabonese children”. PLOS One. 2(4): e389 | por |
| dc.identifier.issn | 1932-6203 | |
| dc.identifier.uri | http://hdl.handle.net/10400.7/214 | |
| dc.identifier.uri | http://dx.doi.org/10.1371/journal.pone.0000389 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Public Library of Science | por |
| dc.relation.publisherversion | http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0000389 | por |
| dc.subject | Immunoglobulin G/immunology | por |
| dc.subject | Malaria, Cerebral/immunology | por |
| dc.subject | Malaria, Falciparum/immunology | por |
| dc.subject | Spectrin/immunology | por |
| dc.title | Self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in Gabonese children | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | San Francisco, CA, USA | por |
| oaire.citation.endPage | e389 | por |
| oaire.citation.startPage | e389 | por |
| oaire.citation.title | PLOS One | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |