Noncanonical Biogenesis of Centrioles and Basal Bodies

Nabais, Catarina; Pereira, Sónia Gomes; Bettencourt-Dias, Mónica

Publication

Noncanonical Biogenesis of Centrioles and Basal Bodies

2018-04Preprint

dc.contributor.author	Nabais, Catarina
dc.contributor.author	Pereira, Sónia Gomes
dc.contributor.author	Bettencourt-Dias, Mónica
dc.date.accessioned	2018-05-17T15:57:10Z
dc.date.available	2018-05-17T15:57:10Z
dc.date.issued	2018-04
dc.description	The deposited article is a pre-print version.	pt_PT
dc.description	The deposited article version is the Epub Ahead of Print version of the article, posted online 23 April 2018, provided by Cold Spring Harbor Laboratory Press. It hasn't peer-review.	pt_PT
dc.description	This deposit is composed by the main article, and it hasn't any supplementary materials associated.	pt_PT
dc.description.abstract	Centrioles and basal bodies (CBBs) organize centrosomes and cilia within eukaryotic cells. These organelles are composed of microtubules and hundreds of proteins performing multiple functions such as signaling, cytoskeleton remodeling, and cell motility. The CBB is present in all branches of the eukaryotic tree of life and, despite its ultrastructural and protein conservation, there is diversity in its function, occurrence (i.e., presence/absence), and modes of biogenesis across species. In this review, we provide an overview of the multiple pathways through which CBBs are formed in nature, with a special focus on the less studied, noncanonical ways. Despite the differences among each mechanism herein presented, we highlighted some of their common principles. These principles, governing different steps of biogenesis, ensure that CBBs may perform a multitude of functions in a huge diversity of organisms but yet retained their robustness in structure throughout evolution.	pt_PT
dc.description.sponsorship	European Research Council Consolidator Grant: (CoG683528__Centriole-BirthDeath); Boehringer Ingelheim Fonds; Fundação para a Ciência e Tecnologia grant: (PD/BD/114350/2016).	pt_PT
dc.description.version	info:eu-repo/semantics/acceptedVersion	pt_PT
dc.identifier.citation	SYMPOSIUM - Early Release Article: Noncanonical Biogenesis of Centrioles and Basal Bodies Catarina Nabais, Sónia Gomes Pereira, and Mónica Bettencourt-Dias Cold Spring Harb Symp Quant Biol 034694Published in Advance April 23, 2018, doi:10.1101/sqb.2017.82.034694	pt_PT
dc.identifier.doi	10.1101/sqb.2017.82.034694	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.7/869
dc.language.iso	eng	pt_PT
dc.peerreviewed	no	pt_PT
dc.publisher	Cold Spring Harbor Laboratory Press	pt_PT
dc.relation	Mechanism of centriole inheritance and maintenance
dc.relation	Origins and fate of plant centrioles
dc.relation.publisherversion	http://symposium.cshlp.org/content/early/2018/04/21/sqb.2017.82.034694.abstract	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	pt_PT
dc.subject	Centrioles	pt_PT
dc.subject	Biogenesis	pt_PT
dc.subject	Basal Bodies	pt_PT
dc.subject	deuterosomes	pt_PT
dc.title	Noncanonical Biogenesis of Centrioles and Basal Bodies	pt_PT
dc.type	preprint
dspace.entity.type	Publication
oaire.awardTitle	Mechanism of centriole inheritance and maintenance
oaire.awardTitle	Origins and fate of plant centrioles
oaire.awardURI	info:eu-repo/grantAgreement/EC/H2020/683258/EU
oaire.awardURI	info:eu-repo/grantAgreement/FCT//PD%2FBD%2F114350%2F2016/PT
oaire.citation.endPage	54	pt_PT
oaire.citation.startPage	1	pt_PT
oaire.citation.title	Cold Spring Harbor Symposia on Quantitative Biology	pt_PT
oaire.fundingStream	H2020
project.funder.identifier	http://doi.org/10.13039/501100008530
project.funder.identifier	http://doi.org/10.13039/501100001871
project.funder.name	European Commission
project.funder.name	Fundação para a Ciência e a Tecnologia
rcaap.rights	openAccess	pt_PT
rcaap.type	preprint	pt_PT
relation.isProjectOfPublication	9524832a-429e-46b4-91fa-73b869fbc551
relation.isProjectOfPublication	873e30b1-ada3-4791-8138-1e22684a7626
relation.isProjectOfPublication.latestForDiscovery	9524832a-429e-46b4-91fa-73b869fbc551