Publication
Genetics. Sowing the seeds of centromeres.
| dc.contributor.author | Jansen, L. E. T. | |
| dc.date.accessioned | 2016-05-24T11:10:36Z | |
| dc.date.available | 2016-05-24T11:10:36Z | |
| dc.date.issued | 2012-01-20 | |
| dc.description.abstract | The centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior? | pt_PT |
| dc.identifier.citation | Jansen, L. E. T. (2012). Genetics. Sowing the seeds of centromeres. Science, 335(6066), 299–300. | pt_PT |
| dc.identifier.doi | 10.1126/science.1218162 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.7/615 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | American Association for the Advancement of Science | pt_PT |
| dc.relation | Documento não apresenta financiadores ou patrocionadores envolvidos. | pt_PT |
| dc.relation.publisherversion | http://science.sciencemag.org/content/335/6066/299.full | pt_PT |
| dc.subject | Animals | pt_PT |
| dc.subject | Centromere | pt_PT |
| dc.subject | Drosophila | pt_PT |
| dc.subject | Histones | pt_PT |
| dc.title | Genetics. Sowing the seeds of centromeres. | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 300 | pt_PT |
| oaire.citation.issue | 6066 | pt_PT |
| oaire.citation.startPage | 299 | pt_PT |
| oaire.citation.title | Science | pt_PT |
| oaire.citation.volume | 335 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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