A carregar...
Publicação
Q&A: Who needs a centrosome?
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| artigo principal | 626.15 KB | Adobe PDF |
Autores
Orientador(es)
Resumo(s)
The centrosome has several functions. The central one
is as the major microtubule organizing center (MTOC)
in proliferating animal cells: thus, it helps to organize the
microtubules that form the mitotic spindle in dividing
cells, and orchestrate a wide variety of cellular processes,
including cell motility, signaling, adhesion, coordination of
protein trafficking by the microtubule cytoskeleton and
the acquisition of polarity. The centrosome has crucial
links to the nucleus, the Golgi, cell to cell junctions and
acto-myosin cytoskeleton that are very important in
positioning it and thus shaping the microtubule cytoskeleton
in relation to the cell and the organism (reviewed in [1]).
The role of the centrosome in organizing cellular
microtubules can differ from cell to cell and be regulated
differently in different phases of the life of a cell.
Descrição
Palavras-chave
Centrosome
Contexto Educativo
Citação
Bettencourt-Dias M: Q&A: Who needs a centrosome?. BMC Biology 2013 11:28.
Editora
BioMed Central