Publication
Q&A: Who needs a centrosome?
| dc.contributor.author | Bettencourt-Dias, Mónica | |
| dc.date.accessioned | 2015-10-22T15:12:14Z | |
| dc.date.available | 2015-10-22T15:12:14Z | |
| dc.date.issued | 2013-04-11 | |
| dc.description.abstract | The centrosome has several functions. The central one is as the major microtubule organizing center (MTOC) in proliferating animal cells: thus, it helps to organize the microtubules that form the mitotic spindle in dividing cells, and orchestrate a wide variety of cellular processes, including cell motility, signaling, adhesion, coordination of protein trafficking by the microtubule cytoskeleton and the acquisition of polarity. The centrosome has crucial links to the nucleus, the Golgi, cell to cell junctions and acto-myosin cytoskeleton that are very important in positioning it and thus shaping the microtubule cytoskeleton in relation to the cell and the organism (reviewed in [1]). The role of the centrosome in organizing cellular microtubules can differ from cell to cell and be regulated differently in different phases of the life of a cell. | pt_PT |
| dc.description.sponsorship | Laboratório Associado de Oeiras, EMBO Installation Grant: (co-funded by FCT and Instituto Gulbenkian de Ciência), FCT, Instituto Gulbenkian de Ciência. | pt_PT |
| dc.identifier | 10.1186/1741-7007-11-28 | |
| dc.identifier.citation | Bettencourt-Dias M: Q&A: Who needs a centrosome?. BMC Biology 2013 11:28. | pt_PT |
| dc.identifier.doi | 10.1186/1741-7007-11-28 | |
| dc.identifier.uri | http://hdl.handle.net/10400.7/428 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | BioMed Central | pt_PT |
| dc.relation | Control of Centriole Structure And Number | |
| dc.relation.publisherversion | http://www.biomedcentral.com/1741-7007/11/28 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Centrosome | pt_PT |
| dc.title | Q&A: Who needs a centrosome? | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Control of Centriole Structure And Number | |
| oaire.awardURI | info:eu-repo/grantAgreement/EC/FP7/261344/EU | |
| oaire.citation.endPage | 7 | pt_PT |
| oaire.citation.issue | 1 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | BMC Biology | pt_PT |
| oaire.citation.volume | 11 | pt_PT |
| oaire.fundingStream | FP7 | |
| project.funder.identifier | http://doi.org/10.13039/501100008530 | |
| project.funder.name | European Commission | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isProjectOfPublication | 0faa6bb2-99b3-4582-9b24-873d528eceb3 | |
| relation.isProjectOfPublication.latestForDiscovery | 0faa6bb2-99b3-4582-9b24-873d528eceb3 |