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Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant
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Orientador(es)
Resumo(s)
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.
Descrição
The deposited article is a post-print version and has peer review. This deposit is composed by the main article, and it hasn't any supplementary materials associated. There is no public supplementary material available.
Palavras-chave
centromere CENP-A histone kinetochore CenH3
Contexto Educativo
Citação
Earnshaw, W.C., Allshire, R.C., Black, B.E. et al. Chromosome Res (2013) 21: 101. https://doi.org/10.1007/s10577-013-9347-y
Editora
Springer Verlag