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Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

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The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

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The deposited article is a post-print version and has peer review. This deposit is composed by the main article, and it hasn't any supplementary materials associated. There is no public supplementary material available.

Keywords

centromere CENP-A histone kinetochore CenH3

Citation

Earnshaw, W.C., Allshire, R.C., Black, B.E. et al. Chromosome Res (2013) 21: 101. https://doi.org/10.1007/s10577-013-9347-y

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