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Publication
How Inflammation Impinges on NAFLD: A Role for Kupffer Cells
| Name: | Description: | Size: | Format: | |
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| main article | 1.66 MB | Adobe PDF |
Advisor(s)
Abstract(s)
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of liver disease worldwide and afflicts adults and children as currently associated with obesity and insulin resistance. Even though lately some advances have been made to elucidate the mechanism and causes of the disease much remains unknown about NAFLD. The aim of this paper is to discuss the present knowledge regarding the pathogenesis of the disease aiming at the initial steps of NAFLD development, when inflammation impinges on fat liver deposition. At this stage, the Kupffer cells attain a prominent role. This knowledge becomes subsequently relevant for the development of future diagnostic, prevention, and therapeutic options for the management of NAFLD.
Description
This deposit is composed by the main article, and it hasn't any supplementary materials associated.
This deposit is composed by a publication in which the IGC's authors have had the role of collaboration (it's a collaboration publication). This type of deposit in ARCA is in restrictedAccess (it can't be in open access to the public), and can only be accessed by two ways: either by requesting a legal copy from the author (the email contact present in this deposit) or by visiting the following link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450298/
This deposit is composed by a publication in which the IGC's authors have had the role of collaboration (it's a collaboration publication). This type of deposit in ARCA is in restrictedAccess (it can't be in open access to the public), and can only be accessed by two ways: either by requesting a legal copy from the author (the email contact present in this deposit) or by visiting the following link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450298/
Keywords
Inflammation Kupffer Cells
Citation
Nádia Duarte, Inês C. Coelho, Rita S. Patarrão, Joana I. Almeida, Carlos Penha-Gonçalves, and M. Paula Macedo, “How Inflammation Impinges on NAFLD: A Role for Kupffer Cells,” BioMed Research International, vol. 2015, Article ID 984578, 11 pages, 2015. doi:10.1155/2015/984578
